Charming family photographs are interspersed with celebrity friends like Henry Fonda and Errol Flynn. In one photo, Wyeth is fencing with Douglas Fairbanks Jr.; in the next room, fencing masks line a windowsill and phone numbers are jotted down on a wall next to the telephone. There are collections of World War I uniforms and helmets, Sheperd Paine dioramas, shelves upon shelves of art books, stacked film canisters and 1,250 military figurines -- some from Wyeth's childhood and subjects of his earliest drawings.
An old film projector in what once was the living room points to the wall where the family frequently watched the epic World War I silent movie "The Big Parade," Wyeth's favorite film. Its landscapes and other imagery made their way into his paintings.
In the same room is a re-creation of the little cordoned-off workspace, created by a then-teenage Jamie Wyeth with a couple of black fabric partitions, where he would paint his famous posthumous portrait of John F. Kennedy in 1967, among other works.
"A lot of what we relied on is oral history," Podmaniczky said. "They were not a family who took a lot of photographs."
The main space where Wyeth did his actual painting is the most bare in the house. The unpainted plaster walls are adorned only with sketches and studies for his paintings and a few photos, while the dominant features are a huge mirror, paint-stained apron, round stool and brushes.
Long cracks run along the ceiling and a plywood sheet covers one window, concentrating the sunshine through the north-facing windows that brought the best light.
"He was very unassuming," Podmaniczky said. "The trappings didn't matter. He just wanted to paint."
Next to an artist's palette sits an egg crate for making his signature medium -- egg tempera, a thick mixture of yolks, pigment and distilled water. Mary Nell Ferry, a guide who will walk visitors through the site, said the famous artist's preferred eggs came from a local convenience store.
"He always used Wawa extra-large eggs for his egg tempera," she said. "They had to be white eggs because he thought brown eggs had an oilier consistency."
At the Brandywine River Museum, a companion exhibit brings together works featuring architectural elements and objects visitors will recognize after touring Wyeth's studio.