The analysis covers 1992-2010. Participants were mostly in their 50s at the study's beginning and were asked about their job history, and about employment status and recent heart attacks at subsequent interviews. People who'd had heart attacks before the study began were excluded.
Nearly 70 percent had at least one job loss, or period of unemployment after working at a job, and at least 10 percent had four or more before and/or during the study period.
There were 1,061 heart attacks during the study. Those with at least one job loss were 22 percent more likely to have a heart attack than those who never lost a job. Those with at least four job losses had a 60 percent higher risk than those with none. Men and women faced equal risks.
Even though the odds linked with job loss weren't huge, many participants already faced increased other risks for a heart attack because of obesity, high blood pressure or lack of exercise.
"Any significant additional risk is important," Dupre said.
Heart attack risk calculator: http://bit.ly/PZxWtH