"We have an aggressive operation and ground game in place," campaign spokesman Rick Gorka said.
The state GOP is set to begin running a television ad Friday assailing Obama's economic leadership. Pennsylvania's unemployment rate, at 8.1 percent, is slightly less than the national average.
Obama and Romney are scheduled to face off Wednesday in Denver for the first of three presidential debates, which may represent the challenger's best remaining opportunity to change the trajectory of his campaign. Romney has struggled through a series of perceived missteps in weeks amid signs that confidence in the nation's economy is on the rise.
The Obama campaign released a political memo on Friday saying it expects Romney "to be a prepared, disciplined and aggressive debater."
However, it said that while the president would be laying out his vision for the coming years, Romney has "signaled that he will come to indict the president for the fact that the economy has not fully recovered from the collapse of 2008."
The Obama memo and an accompanying web video also aim to debunk claims by Romney that the president has mischaracterized the Republican's positions on the auto industry bailout, abortion and raising taxes on wage earners to cover tax cuts for multimillionaires.
Obama was expected to meet with advisers Friday to prepare for next week's debate. The president was departing Sunday for Nevada, where he planned to hold debate practice sessions near Las Vegas.
Romney has been focused on fundraising and debate preparation for several weeks, raising some questions from within the GOP about his strategy. Earlier in the week, Romney said the time had come in the campaign when he would start spending less time with donors and more time with voters in swing states.
Following his stop in Pennsylvania, Romney heads to Boston for an evening fundraiser and a weekend focused on more debate preparation.
In an election centered largely on the economy, each side got some new ammunition on Thursday. The Commerce Department lowered its earlier estimate of tepid growth for the April-June quarter, while the Labor Department said the economy added 386,000 more jobs from April 2011 through March 2012 than previously believed.
Romney compared the American economy to that of Russia as he ignored signs of growth and pounced on the Commerce Department's downward revision.
"By the way, Russia's GDP growth is at 4 percent. And we're at 1.3. This is unacceptable," he said. "The president does not understand how to get this economy to work for the American people."