Oklahoma State, Texas Tech and TCU are bowl eligible. Not counting the BCS, the Big 12 has tie-ins to seven bowls and would look for a possible open slot elsewhere if more Big 12 teams than bowls are available.
Iowa State (5-5, 2-5) plays at one-win Kansas on Saturday and finishes the regular season at home against West Virginia on Nov. 23. The Cyclones are looking for their second straight bowl appearance.
Over the summer, the Oklahoma-West Virginia game was envisioned as having title implications.
Instead, West Virginia (5-4, 2-4) is fighting to keep a 10-year streak of going to bowls intact. The Mountaineers have lost four straight games, their longest losing streak in 11 years.
West Virginia coach Dana Holgorsen still envisions Oklahoma's first visit to Morgantown as exciting, especially for the fans.
"They've had it circled for a while because OU is such a storied program,'' Holgorsen said.
In addition to playing Oklahoma and Iowa State, West Virginia finishes the regular season at home Dec. 1 against Kansas.
Baylor (4-5, 1-5) needs two wins in its final three games to have the chance of going to an unprecedented third straight bowl.
The Bears' uphill trek starts Saturday at home against Kansas State, followed by a Nov. 24 matchup with No. 23 Texas Tech at Cowboys Stadium in Arlington, and a Dec. 1 home game against Oklahoma State.