The Wildcats (8-16), who trailed 22-16 at halftime, received 11 points from A.J. Reynolds.
Wes Mitchem scored 22 points, Logan Cox 18 and Doug Dennis 12 for South, which hosts University at 7 p.m. Tuesday.
Andrew Kowalo contributed 12, Ryan Reinbeau 11 and Luke Saseen 10 for Wheeling Park, which visits Morgantown at 7 p.m. Tuesday.
Hunter Given added 24 points for Webster, which faces the Fairmont Senior-North Marion loser at 7 p.m. Wednesday at Webster.
Anderson Davis scored 25 for Ritchie, which visits the Fairmont Senior-North Marion winner at 7 p.m. Wednesday.
Mikey Newsome added 17 points for the Panthers and Aaron Muncy had 13. Keith Mullins paced Greater Beckley Christian with 20 points.
For the Region 3 co-finals on Thursday, Tug Valley hosts Greenbrier West and Greater Beckley travels to Valley.
Levi Beck added 10 points and seven rebounds for the Cougars (12-9), who will play Moorefield at 7 p.m. today at Petersburg for the section title.
Logan Raines and Hayden Fox each scored six points to lead Pendleton County.