With her nine blocks, Griner increased her career total to 651, 13 shy of breaking the NCAA career record.
"We turned them over like we felt we could 19 times. We didn't get out-rebounded that bad and we tried not to miss foul shots and limit our turnovers, but Brittney (Griner) hit some big shots," Carey said. "She just opens up so many more people on the floor that you really wouldn't have to help off of, but then they become effective and start getting hot."
Baylor's home winning streak includes an 82-68 win over West Virginia in an NCAA tournament second-round game two years ago. Griner had 30 points and eight blocks in that game, even while sitting out the last 9 minutes of the first half after two fouls.
West Virginia ended Baylor's big run with six points in a row in a span of 36 seconds, capped by Caldwell and Jess Harlee turning consecutive steals into breakaway baskets in only 15 seconds.
But Griner quickly responded with six points in a row of her own and by the next timeout with 8 minutes left in the first half, Griner already had 16 points - one more than West Virginia at the time, when Baylor led 26-15.
The Mountaineers had won three in a row since opening their first Big 12 schedule with losses against Oklahoma and Kansas.
Ayana Dunning, who was averaging 10.8 points a game for West Virginia, finished scoreless with four fouls in 23 minutes. She was 0-for-8 shooting, including five from 3-point range.
West Virginia sophomore guard Akilah Bethel was carried off the court with just more than 2 minutes to go. She grabbed her left knee after falling to the floor on a drive to the basket, though the extent of her injury wasn't immediately known.